Searchable abstracts of presentations at key conferences in endocrinology

ea0022oc3.6 | Pituitary | ECE2010

Young patients with sporadic macroadenomas as target population for AIP mutations screening

Tichomirowa Maria , Barlier Anne , Daly Adrian , Jaffrain-Rea Marie-Lise , Cozzi Renato , Yaneva Maria , Naves Luciana , Ronchi Christina , Sievers Caroline , Maiter Dominique , Montanana Carmen Fajardo , Zacharieva Sabine , Beckers Albert

Methods: We undertook an assessment of patients which were diagnosed with or had their first symptoms of pituitary tumor before the age of 30 and had tumor diameter more than 1 cm without familial history of pituitary adenomas. In patients that consented to genetic analysis, germline mutations in the AIP gene were sought.Results: The study population consisted of 164 patients (61 prolactinomas, 84 somatotropinomas, 16 non-secreting tumors, two pat...